N-[(S)-Ethoxycarbonyl-1-Butyl]-(S)-Alanine

Product Overview

N-[(S)-Ethoxycarbonyl-1-Butyl]-(S)-Alanine is a critical chiral intermediate utilized extensively in the pharmaceutical industry for the synthesis of advanced therapeutic agents. Specifically designed for high-efficiency coupling reactions, this compound serves as a foundational building block in the production of Angiotensin-Converting Enzyme (ACE) inhibitors. Our manufacturing process ensures exceptional stereochemical integrity, maintaining the (S,S) configuration required for biological activity in downstream API production. We specialize in delivering this intermediate with consistent quality parameters to support large-scale pharmaceutical manufacturing needs.

Key Specifications

Industrial Applications

This specialized intermediate is primarily employed in the multi-step synthesis of Perindopril, a widely prescribed medication for managing hypertension and heart failure. The unique ethoxycarbonyl protection group facilitates selective amidation processes while preserving the chiral center essential for pharmacological efficacy. Pharmaceutical manufacturers rely on this compound for its stability during storage and reactivity under standard peptide coupling conditions. Our supply chain supports both clinical trial material requirements and commercial-scale API production, ensuring seamless integration into your existing synthesis routes without compromising yield or purity profiles.

Quality Assurance And Control

Quality is paramount in pharmaceutical intermediate production. Every batch of N-[(S)-Ethoxycarbonyl-1-Butyl]-(S)-Alanine undergoes rigorous analytical testing using High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy. We verify enantiomeric excess to guarantee the correct stereochemistry, which is vital for the safety and efficacy of the final drug product. Our facilities adhere to strict quality management systems, providing comprehensive Certificates of Analysis (COA) with each shipment. We maintain traceability from raw material sourcing to final packaging, ensuring compliance with international regulatory standards for pharmaceutical ingredients.

Packaging And Storage

To maintain product integrity during transit and storage, this intermediate is packaged in durable 25 kg drums lined with moisture-resistant materials. Custom packaging solutions are available upon request to accommodate specific logistical requirements or smaller research quantities. Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and sources of heat. Proper handling procedures should be followed to prevent contamination or degradation. Our global logistics network ensures timely delivery to manufacturing sites worldwide, supported by detailed safety data sheets and technical documentation to facilitate smooth customs clearance and warehouse management.